时 间:2024年5月28日10:00-11:00
地 点:普陀校区理科大楼A1514
报告人:吴浪 加拿大不列颠哥伦比亚大学 教授
主持人:刘玉坤 华东师范大学教授
摘 要:
In a survival model with a time-dependent covariate, the covariate may be
left censored due to a lower detection limit and its observed values may contain
outliers. Motivated from an HIV vaccine study, we propose a robust method
for joint models of longitudinal and survival data, where the outliers in longitudinal
data are addressed using a multivariate t-distribution for b-outliers and
using an M-estimator for e-outliers. We also propose a computationally efficient
method for approximate likelihood inference. The proposed method is
evaluated by simulation studies. Based on the proposed models and method,
we analyze the HIV vaccine data and find a strong association between longitudinal
biomarkers and the risk of HIV infection..
报告人简介:
吴浪,加拿大不列颠哥伦比亚大学 统计系终身教授。华东师范大学数学系本科、硕士,华盛顿大学统计学博士,哈佛大学生物统计学博士后。研究方向包括纵向(面板)数据分析、缺失数据分析、生存分析、多元分析、生物统计等。在JASA、Statistical Science、Biometrics、Biostatistics等国际统计杂志上发表80多篇论文,出版专著2本。主持多项加拿大国家自然科学基金项目。